Integrated Analysis of Cancer Tissue and Vitreous Humor from Retinoblastoma Eyes Reveals Unique Tumor-Specific Metabolic and Cellular Pathways in Advanced and Non-Advanced Tumors.
Authors: Vishnu Suresh Babu 1 2, Ashwin Mallipatna 3, Deepak Sa 4, Gagan Dudeja 3, Ramaraj Kannan 1, Rohit Shetty 1, Archana Padmanabhan Nair 1, Seetharamanjaneyulu Gundimeda 4, Shyam S Chaurasia 5, Navin Kumar Verma 6 7, Rajamani Lakshminarayanan 7, Stephane Heymans 2 8, Veluchamy A Barathi 7 9 10, Nilanjan Guha 4, Arkasubhra Ghosh […]
Treatment of glaucoma by prostaglandin agonists and beta-blockers in combination directly reduces pro-fibrotic gene expression in trabecular meshwork
Authors: Sushma Tejwani , Praveen Machiraju, Archana Padmanabhan Nair , Anuprita Ghosh , Raunak Kumar Das, Arkasubhra Ghosh , Swaminathan Sethu Keywords: NA PMID: 32267082 DOI: 10.1111/jcmm.15172
Comparison of Structural, Functional, Tonometric, and Visual Acuity Testing for Glaucoma: A Prospective Diagnostic Accuracy Study
Authors: Rajesh S Kumar 1, B Ramgopal 2, Mahalakshmi V Rackenchath 2, Sathi Devi A V 2, Suria S Mannil 3, Sriharsha Nagaraj 2, Caitlin A Moe 4, Dionna M Wittberg 4, Kieran S O’Brien 4, Robert L Stamper 5, Jeremy D Keenan Keywords: Glaucoma; Intraocular pressure; Sensitivity and specificity; Tomography; Visual fields.Glaucoma; Intraocular pressure; […]
Corneal Confocal Microscopy Features and Tear Molecular Profile in Study Participants with Discordance between Ocular Surface Disease Clinical Signs and Discomfort
Authors: Sharon D’Souza 1, Rohit Shetty 1, Archana Padmanabhan Nair 2 3, Ruchika Agrawal 2, Mor M Dickman 4 5, Pooja Khamar 1, Rudy M M A Nuijts 4, Arkasubhra Ghosh 2, Swaminathan Sethu Keywords: corneal dendritic cells; dry eye disease; in vivo confocal microscopy; microneuromas; ocular surface pain; tear film. PMID: 35566533 DOI: 10.3390/jcm11092407
Ocular Surface Infection Mediated Molecular Stress Responses: A Review
Authors: Samayitree Das 1, Sharon D’Souza 2, Bhavya Gorimanipalli 2, Rohit Shetty 2, Arkasubhra Ghosh 1, Vrushali Deshpande Keywords: bacterial conjunctivitis; bacterial keratitis; fungal conjunctivitis; fungal keratitis; gene expression; host stress response; ocular surface infections; proteins; viral conjunctivitis; viral keratitis. PMID: 35328532 DOI: 10.3390/ijms23063111
Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019
Authors: NK cells; SARS-CoV-2; T cells; immune therapy; induced pluripotent stem cells; lung epithelial cells; organoids. Keywords: NK cells; SARS-CoV-2; T cells; immune therapy; induced pluripotent stem cells; lung epithelial cells; organoids. PMID: 34656419 DOI: 10.1016/j.jcyt.2021.08.003
Upregulated NOTCH Signaling in the Lens of Patients With Pseudoexfoliation Syndrome Compared With Pseudoexfoliation Glaucoma Suggests Protective Role
Authors: Zia S Pradhan 1, Shivani Dixit 1, Lekshmi Krishna 2, Reshma Shetty 2, Sushma Tejwani 1, Harsha L Rao 1, Rohit Shetty 3, Carroll A B Webers 4, Debashish Das Keywords: NA PMID: 35210385 DOI: 10.1097/IJG.0000000000001975
Trends in teleconsultations for uveitis during the COVID-19 lockdown
Authors: Padmamalini Mahendradas 1, Swaminathan Sethu 2, Chaitra Jayadev 3, Aaditi Anilkumar 1, Ankush Kawali 1, Srinivasan Sanjay 1, Sai Bhakti Mishra 1, Rohit Shetty 4, Bhujang K Shetty Keywords: COVID-19 pandemic; India; lockdown; teleconsultation; telemedicine; teleophthalmology; uveitis; video consultation. PMID: 35225562 DOI: 10.4103/ijo.IJO_1759_21
Quantitative Proteomics Reveals Molecular Network Driving Stromal Cell Differentiation: Implications for Corneal Wound Healing
Authors: Krishnatej Nishtala1, Trailokyanath Panigrahi1, Rohit Shetty2, Dhanananajay Kumar1, Pooja Khamar, Rajiv R. Mohan3,4,5,6 Vrushali Deshpande1, and Arkasubhra Ghosh1 Keywords: cornea; wound healing; TGF-β; keratocytes; fibroblasts; myofibroblasts; quantitative proteomics; LCMS; SLIT-ROBO signaling; integrin signaling; actin cytoskeleton; calcium signaling PMID: 35269714 DOI: 10.3390/ijms23052572
Biochemical and molecular alterations and potential clinical applications of biomarkers in keratoconus
Authors: Vaitheeswaran G Lalgudi 1, Rohit Shetty 2, Kanwal K Nischal 3 4, Setareh Ziai 1 5, Mona Koaik 1 5, Swaminathan Sethu Keywords: Biochemical markers; cyclosporine; inflammation; keratoconus; personalized medicine. PMID: 35971485 DOI: 10.4103/SJOPT.SJOPT_203_21