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nVault Categories: GROW - Gene Therapy

Enhanced Epithelial-to-Mesenchymal Transition and Chemoresistance in Advanced Retinoblastoma Tumors Is Driven by miR-181a

Authors: Vishnu Suresh Babu 1 2, Anadi Bisht 1, Ashwin Mallipatna 3, Deepak Sa 4, Gagan Dudeja 3, Ramaraj Kannan 1, Rohit Shetty 1, Nilanjan Guha 4, Stephane Heymans 2 5, Arkasubhra Ghosh 1 Keywords: EMT; chemo-resistant; miRNA; retinoblastoma. PMID: 36291907 DOI: 10.3390/cancers14205124

Lack of Retinoblastoma Protein Shifts Tumor Metabolism from Glycolysis to OXPHOS and Allows the Use of Alternate Fuels

Authors: Vishnu Suresh Babu 1 2, Gagan Dudeja 3, Deepak Sa 4, Anadi Bisht 1, Rohit Shetty 1, Stephane Heymans 2 5, Nilanjan Guha 4, Arkasubhra Ghosh 1 Keywords: OCR; OXPHOS; energetics; glycolysis; metabolism; retinoblastoma PMID: 36291051 DOI: 10.3390/cells11203182

Unique corneal tomography features of allergic eye disease identified by OCT imaging and artificial intelligence

Authors: Himanshu Matalia , Jyoti Matalia , Anchana Pisharody , Yash Patel , Nandini Chinnappaiah , Marcella Salomao , Renato Ambrosio , Abhijit Sinha Roy Keywords: NA PMID: 32649048 DOI: 10.1002/jbio.202000156

Clinical and Molecular Outcomes After Combined Intense Pulsed Light Therapy With Low-Level Light Therapy in Recalcitrant Evaporative Dry Eye Disease With Meibomian Gland Dysfunction

Authors: Sharon D’Souza 1, Archana Padmanabhan Nair 2, Gowtham Iyappan 2, Mor M Dickman 3, Prashansa Thakur 1, Ritika Mullick 1, Gairik Kundu 1, Swaminathan Sethu 2, Arkasubhra Ghosh 2, Rohit Shetty 1 Keywords: NA PMID: 34907942 DOI: 10.1097/ICO.0000000000002954

Mapping of corneal birefringence in thin and asymmetric keratoconus corneas with ultrahigh-resolution polarization-sensitive OCT

Authors: Rahul Patil 1, Rohit Shetty, Raghav Narasimhan, Yash Patel, Pooja Khamar, Michael Pircher, Christoph K Hitzenberger, Rudy M M A Nuijts, Abhijit Sinha Roy Keywords: NA PMID: 35082233 DOI: 10.1097/j.jcrs.0000000000000898

Advancing precision medicines for ocular disorders: Diagnostic genomics to tailored therapies

Authors: Priyalakshmi Panikker 1, Shomereeta Roy 1, Anuprita Ghosh 1, B Poornachandra 2, Arkasubhra Ghosh 1 Keywords: adeno-associated virus; gene therapy; genetic testing; non-viral vectors; ocular dystrophies; ophthalmology; viral vectors. PMID: 35911417 DOI: 10.3389/fmed.2022.906482

Generation of iPSC line (GLNNFi001-A) from peripheral blood mononuclear cells of a patient with macular corneal dystrophy

Authors: Koushik Chakrabarty 1, K N Prashanthi 2, Rohit Shetty 3, Shubham Argulwar 2, Nallathambi Jeyabalan 4, Arkasubhra Ghosh 4 Keywords: NA PMID: 35472829 DOI: 10.1016/j.scr.2022.102789

Trials and tribulations of rare eye diseases

Authors:Rohit Shetty 1, Swaminathan Sethu 1, Chaitra Jayadev 1 Keywords: NA PMID: 35791096 DOI: 10.4103/ijo.IJO_782_22

Rare eye diseases in India: A concise review of genes and genetics

Authors: Nallathambi Jeyabalan 1, Anuprita Ghosh 1, Grace P Mathias 1, Arkasubhra Ghosh 1 Keywords: Genetic analysis, genetic counseling, next-generation sequencing, rare eye diseases PMID: 35791102 DOI: 10.4103/ijo.IJO_322_22

Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease

Authors: Meysam Yazdankhah , Peng Shang , Sayan Ghosh , Imran A Bhutto , Nadezda Stepicheva , Rhonda Grebe, Stacey Hose, Joseph Weiss 1, Tianqi Luo , Subrata Mishra , S Amer Riazuddin , Arkasubhra Ghosh , James T Handa , Gerard A Lutty , J Samuel Zigler Jr , Debasish Sinha Keywords: NA PMID: […]

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nVision by Narayana Netralaya Foundation (NNF) bridges the gap from “bench to clinic” by integrating GROW’s molecular research with IBMS’s advanced imaging. This synergy transforms vast patient data into real-time diagnostic and therapeutic solutions, delivering cutting-edge, personalized healthcare to the world.

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