Efficiency of different fragment lengths of the ubiquitous chromatin opening element HNRPA2B1-CBX3 in driving human CD18 gene expression within self-inactivating lentiviral vectors for gene therapy applications

Authors: Chitra Gopinath 1, Sarvani Chodisetty 1, Arkasubhra Ghosh 2, Everette Jacob Remington Nelson

Keywords: CD18; Gene therapy; Hematopoietic stem cells (HSCs); Lentiviral vectors; Leukocyte adhesion deficiency type 1 (LAD1); Ubiquitous chromatin opening element (UCOE)

PMID: 31200085

DOI: 10.1016/j.gene.2019.06.016