Cancer stem cell mediated acquired chemoresistance in head and neck cancer can be abrogated by aldehyde dehydrogenase 1 A1 inhibition

Authors: Safeena Kulsum 1 2, Holalugunda Vittalamurthy Sudheendra 1, Ramanan Pandian 3, Doddathimmasandra Ramanjanappa Ravindra 4, Gangotri Siddappa 1, Nisheena R 5, Priyanka Chevour 3, Balaji Ramachandran 6, Milind Sagar 6, Aravindakshan Jayaprakash 6, Alka Mehta 2, Vikram Kekatpure 4, Naveen Hedne 4, Moni A Kuriakose 1 4 7, Amritha Suresh 1 4 7

Keywords: ALDH1A1; cancer stem cells; cross resistance; drug resistant cell lines; head and neck cancer.

PMID: 27380877

DOI: 10.1002/mc.22526